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4-Androstenediol


This popular prohormone to testosterone was banned for sale in early 2005.  It converted to testosterone at about 15-40% and was a very common prohormone in many products. It was introduced to the market by Patrick Arnold and was supposed to be an improvement over 4-Androstenedione because it had less chance of being converted to estrogen and additionally, had some intrinsic anabolic activity.

4-Androstenediol was never a potent prohormone on it’s own, but was commonly stacked with other prohormones like 1-Androstenediol because it was a “wet” prohormone.  The term “wet” means that it could convert to estrogen and added in some blood pressure lowering qualities along with a small amount of bloat.

4-Androstenediol was sold in 25-250 mg capsules and the typical dose required to have an effect was typically about 600mg.  It was never considered a huge mass builder on it’s own, but it was one of the most popular prohormones on the market.

Long before improvements in the understanding of prohormone conversion, 4-Androstenediol was introduced in a variety of delivery systems that improved it’s bioavailability.  Topical 4-Androstenediol and sublingual 4-Androstenediol were very popular because they passed the intestinal tract and provided better converstion to testosterone.  4-Androstenediol esters and ethers were also popular, since these functional groups gave the hormone the abilty to be picked up by the lymph fluid and delivered in a much better way than standard 4-Androstenediol that was absorbed orally in the gut.

The side effects of 4-Androstenediol were bloating, hairloss, possible gynocomastia and agression. These side effects were common, due to the lack of understanding about prohormone conversion.  4-Androstenediol is still legal in some countries and may still be found there.  It was never the best choice as a prohormone, but it was a significant advancement over standard dione preperations.

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